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Hiroshi Handa graduated from Keio University School of Medicine in 1972 and received his doctorate from the same institution in 1976, before moving onto the University of Tokyo, Institute of Medical Science as a research associate in the same year. From 1978 to 1980 he moved to the US where he worked under Dr. Phillip A Sharp at the Massachusetts Institute of Technology, studying the in vitro transcription of SV40 and adenovirus genes. Moving back to Japan he took up an associate professorship at University of Tokyo in 1984 and started developing functional latex nano-particles as a substitute for conventional agarose beads, for use in affinity screening. He joined the Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology as a full professor in 1991, where he has been responsible for expanding nanoparticle technology into both basic and applied science. From 1994 to 1999 Dr. Handa took a visiting professorship at National Institute of Genetics, and has held a similar visiting position at Keio University School of Medicine and Tokyo Medical and Dental University from 2001. As a project leader in the METI program from 1998 to 2003 his research looked at “Technologies for creating new bioaffinity molecules using submicron beads,” and a further METI program from 2003 to 2006 examined “Screening project using nanoparticle technology.” He is also a leader of the 21st Center of Excellence program, dating from 2002 to 2007. His recent research focuses on (1) regulation of transcription elongation of RNA polymerase II; (2) construction of functional latex or magnetic nanoparticles and their applications; (3) chemical biology/chemical genetics; (4) preparation of functional nano-capsules with viral capsid proteins and their applications. |
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