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| Filippo Rijli is Research Director at the Institut de Genetique et Biologie Moleculaire et Cellulaire (IGBMC) in Strasbourg, France, where he serves as Deputy Coordinator of the Department of Developmental Biology. After a pre–doctoral stage at NIH in Bethesda, USA, he received his PhD in Evolutionary and Developmental Biology from the University of Pisa, Italy, working with Giuseppina Barsacchi. He then moved to Strasbourg to do his post–doctoral work with Pierre Chambon. Since 1997, he has served as Group Leader at IGBMC and holds a permanent appointment from the Centre National de la Recherche Scientifique (CNRS). He is on the editorial board of Development and is a member of the Faculty of 1000, Section of Developmental Biology. His research centers on the genetic and molecular analysis of hindbrain patterning and craniofacial morphogenesis in the vertebrate embryo, with a focus on the developmental role of Hox genes. He generated the targeted inactivation of the mouse Hoxa2 gene, providing the first experimental demonstration of the homeotic role of a vertebrate Hox gene in patterning the cranial neural crest. He then accomplished the first targeted mutation of a Hox retinoid regulatory element and studied its in vivo requirement in neural expression. More recently, work in his laboratory has focused on the involvement of Hox genes in neuronal patterning and downstream targets. |
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