Past Events
Category |
Seminar |
Date and Time |
2017-11-09 16:00 - 17:00 |
Venue |
Seminar Room A7F |
Speaker |
Sophie Vriz |
Affiliation |
Professor University Paris 7 - Denis Diderot |
Title |
Redox signalling in development and regeneration |
Poster |
click here to download(PDF) |
Host |
Sa-Kan Yoo |
Summary |
Reactive Oxygen Species (ROS) have long been considered toxic compounds. However, recent findings have shown that ROS contribute to bona fide physiological processes, leading to a new paradigm in reversible post translational modifications involved in signal transduction, known as redox signalling. We have developed genetic and optogenetic tools to record and manipulate H2O2 levels during zebrafish development and regeneration. This approach reveals an unexpected relationship between nerve, H2O2 and Shh signalling in morphogenesis and regeneration.
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