The 22nd CDB Meeting RNA Sciences in Cell and Developmental Biology II June 11 - 13, 2012 at RIKEN CDB, Kobe, Japan
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Program
PDF version of the schedule can be downloaded from here. Monday, June 11 (Day 1) Tuesday, June 12 (Day 2) Wednesday, June 13 (Day 3) Poster Program
Monday, June 11 (Day 1)
9:00 am-9:50 am Registration 9:50 am-10:00 am Opening Remarks by Akira Nakamura Keynote Lecture Chair: Toshifumi Inada 10:00 am – 10:40 am K1 RNA Degradation Switches Mitotic Growth to Meiotic Development in Fission Yeast Masayuki Yamamoto (Kazusa DNA Research Institute, Japan) 10:40 am – 11:10 am Coffee Break Session 1 [Small RNA I] Chair: Yukihide Tomari 11:10 am – 11:35 am S1-1 The Role of Noncoding RNAs in Vertebrate Development Antonio Giraldez (Yale University, USA) 11:35 am – 12:00 pm S1-2 The Roles of miRNAs in Cartilage Development and Homoeostasis Hiroshi Asahara (Tokyo Medical and Dental University, Japan) 12:00 pm – 1:00 pm Lunch Session 2 [RNA and Chromatin] Chair: Frank Sauer 1:00 pm – 1:25 pm S2-1 Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions Bing Ren (University of California, San Diego, USA) 1:25 pm – 1:45 pm S2-2 HP1/Swi6 Acts in Concert with Ers1 to Regulate RNAi-directed Heterochromatin Assembly Aki Hayashi (RIKEN Center for Developmental Biology, Japan) 1:45 pm – 2:10 pm S2-3 Novel Roles of the Pre-mRNA Splicing Machinery in the RNAi-mediated Centromeric Gene Silencing Tokio Tani (Kumamoto University, Japan) Poster Introduction 1 Chair: Yuji Kageyama 2:10 pm – 2:40 pm Molecular Function of a Novel RNA Binding Protein in Embryonic and Mature Endoderm Cells (P05) Nicolas Fossat (Children's Medical Research Institute, Australia) Stabilisation of Human Interferon-α1 mRNA by Its Antisense RNA (P23) Tominori Kimura (Ritsumeikan University, Japan) Biogenesis of Small RNAs Associating with Rice MEL1, a Germ-Cell-Specific Argonaute Protein (P25) Reina Komiya (National Institute of Genetics, Japan) Red5: An Essential Factor for Selective Elimination of Meiotic mRNAs in Vegetative Fission Yeast (P45) Tomo Sugiyama (University of Tsukuba, Japan) A Molecular Machinery that Determines Alternative Splicing Patterns of Insulin Receptor in C. elegans Chemosensory Neurons (P51) Masahiro Tomioka (The University of Tokyo, Japan) Translational Regulation of Mouse Interferon Beta mRNA via the AU-Rich Elements, the mRNA Poly(A) Tail and Poly(A)-Binding Protein (P59) Akiko Yanagiya (McGill University, Canada) Poster Session 1 2:40 pm - 4:10 pm Presenters of Odd-numbered posters should be by their panels for discussion from 2:40 pm – 3:25 pm Presenters of Even-numbered posters should be by their panels for discussion from 3:25 pm – 4:10 pm Session 3 [RNA Processing I] Chair: Jun-ichi Nakayama 4:10 pm – 4:35 pm S3-1 A Non-coding RNA Regulates Chromatin-mediated Modulation of Alternative Splicing Reini Luco (Institut de Génétique Humaine, Montpellier, France) 4:35 pm – 4:55 pm S3-2 Canonical A-to-I and C-to-U RNA Editing is Abundant in Multiple Mouse Tissues Tongjun Gu (The Jackson Laboratory, USA) 4:55 pm – 5:20 pm S3-3 Challenges to Congenital Genetic Disorders with "RNA-targeting" Chemical Compounds Masatoshi Hagiwara (Kyoto University, Japan) 5:20 pm – 5:50 pm Coffee Break Session 4 [RNA Development I] Chair: Antonio Giraldez 5:50 pm – 6:15 pm S4-1 Differential Association of gurken and bicoid mRNAs with P Bodies Dictates their Translational States and Establishes the Primary Embryonic Axes Ilan Davis (The University of Oxford, UK) 6:15 pm – 6:40 pm S4-2 Pgc Protects Germ Plasm RNAs from MicroRNA-Mediated Degradation in Drosophila Primordial Germ Cells Akira Nakamura (RIKEN Center for Developmental Biology, Japan) 6:40 pm – 8:30 pm Reception at CDB Salon
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Tuesday, June 12 (Day 2)
Session 5 [Small RNA II] Chair: Akira Nakamura 9:00 am – 9:25 am S5-1 Biogenesis of PIWI-interacting small RNAs in Drosophila Mikiko C. Siomi (The University of Tokyo, Japan) 9:25 am – 9:50 am S5-2 Structural Biology of Essential Proteins in the piRNA Pathway Hiroshi Nishimasu (The University of Tokyo, Japan) 9:50 am – 10:15 am S5-3 Small RNA-mediated Epigenetic Regulation of DNA Elimination in Tetrahymena Kazufumi Mochizuki (Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Austria) 10:15 am – 10:45 am Coffee Break Session 6 [Ribosome] Chair: Haruhiko Siomi 10:45 am – 11:10 am S6-1 Quality Control of Aberrant mRNA and Protein in Eukaryotes Toshifumi Inada (Tohoku University, Japan) 11:10 am – 11:30 am S6-2 40S Subunit Dissociation and Proteasome-dependent RNA Degradation in Nonfunctional 25S rRNA Decay Makoto Kitabatake (Kyoto University, Japan) 11:30 am – 11:55 am S6-3 Genome-Wide Profiling of Translation Initiation and Protein Synthesis Nicholas Ingolia (Carnegie Institution, USA) 11:55 am -1:00 pm Lunch Poster Introduction 2 Chair: Shinichi Nakagawa 1:00 pm - 1:30 pm Identification of Hundreds of UPF1 Targets by Determining the Stability of Whole Transcriptome in Mammalian Cells (P02) Nobuyoshi Akimitsu (The University of Tokyo, Japan) Natural Sense-Antisense Transcripts Originated from zic3-zic6 Locus in Zebrafish (P26) Igor Kondrychyn (Institute of Molecular and Cell Biology, Singapore) CELF Family RNA-binding Protein UNC-75 Regulates Neuron-specific Alternative Splicing in C. elegans (P30) Hidehito Kuroyanagi (Tokyo Medical and Dental University, Japan) Analysis of Intracellular Localization of Viral RNA Sensor, RLR (P36) Koji Onomoto (Chiba University, Japan) In vivo RNA Imaging with Hybridization-sensitive Fluorescent Oligonucleotide Probes (P56) Dan Ohtan Wang (Kyoto University, Japan) Mex-3B, a KH-type RNA-binding Protein, is Required for IL-33 Production in the Development of Allergic Airway Inflammation (P58) Yusuke Yamazumi (The University of Tokyo, Japan) Poster Session 2 1:30 pm - 3:00 pm Presenters of Even-numbered posters should be by their panels for discussion from 1:30 pm – 2:15 pm Presenters of Odd-numbered posters should be by their panels for discussion from 2:15 pm – 3:00 pm Session 7 [Small RNA III] Chair: Alfredo Castello 3:00 pm – 3:25 pm S7-1 MicroRNAs as Components of Transcriptional Regulatory Circuits in Cancer Kevin Struhl (Harvard Medical School, USA) 3:25 pm – 3:50 pm S7-2 Discovery of Female Specific Small RNAs in Preimplantation Embryos Shin Kobayashi (Tokyo Medical and Dental University, Japan) 3:50 pm – 4:10 pm S7-3 miR-9 Functions in Corticogenesis and Subcorticogenesis Shin Aizawa (RIKEN Center for Developmental Biology, Japan) 4:10 pm – 4:40 pm Coffee Break Session 8 [RNA Processing II] Chair: Masatoshi Hagiwara 4:40 pm – 5:05 pm S8-1 New Insights on the Targeting of HAC1/XBP1 mRNA to Endoplasmic Reticulum Stress Signaling Foci Tomás Aragón (Center for Applied Medical Research, Spain) 5:05 pm – 5:25 pm S8-2 Mature mRNA Resplicing in Cancer Cells Postulates Undiscovered Quality Control Mechanism of mRNA in Normal Cells Toshiki Kameyama (Fujita Health University, Japan) 5:25 pm – 5:50 pm S8-3 Pathogenic Exon-trapping by SVA Retrotransposon and Therapeutic Rescue with Antisense Oligonucleotide in Fukuyama Muscular Dystrophy Tatsushi Toda (Kobe University, Japan)
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Wednesday, June 13 (Day 3)
Session 9 [RNA and Development III] Chair: Ilan Davis 9:00 am – 9:25 am S9-1 Post-transcriptional RNA Regulation in the Sexual Differentiation of Mouse Germ Cells Atsushi Suzuki (Yokohama National University, Japan) 9:25 am – 9:45 am S9-2 Bidirectional Control of mRNA Translation and Synaptic Plasticity by the Cytoplasmic Polyadenylation Complex Tsuyoshi Udagawa (University of Massachusetts Medical School, USA) 9:45 am – 10:05 am S9-3 MAPK Signaling and RNA-granules Formation in Fission Yeast Reiko Sugiura (Kinki University, Japan) 10:05 am – 10:35 am Coffee Break Session 10 [RNA and Development IV] Chair: Tetsuro Hirose 10:35 am – 11:00 am S10-1 Role of Long Non-coding RNAs in Development and Disease Frank Sauer (University of California, Riverside, USA) 11:00 am – 11:20 am S10-2 Nuclear Noncoding RNA Neat1 Regulates Corpus Luteum Development in Aged Animals Shinichi Nakagawa (RIKEN Advanced Science Institute, Japan) 11:20 am – 11:45 am S10-3 Insights into RNA Biology from a Mammalian Cell mRNA Interactome Alfredo Castello (European Molecular Biology Laboratory, Germany) 11:45 am – 12:45 pm Lunch Session 11 [Small RNA IV] Chair: Kazufumi Mochizuki 12:45 pm – 1:10 pm S11-1 Biochemical Dissection of RISC Assembly and Function Yukihide Tomari (The University of Tokyo, Japan) 1:10 pm – 1:30 pm S11-2 Crystal Structure of the Eukaryotic RNA-induced Silencing Complex Kotaro Nakanishi (Memorial Sloan-Kettering Cancer Center, USA) 1:30 pm – 1:55 pm S11-3 Maelstrom Functions in both Transposon Silencing and Microtubule Organization in the Drosophila Ovary Haruhiko Siomi (Keio University, Japan) 1:55 pm – 2:05 pm Closing Remarks by Toshifumi Inada
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Poster Program
P01 Transcription Timings Determine the Destiny of Interferon-beta mRNA Stability Kaito Abe (Yokohama City University, Japan) P02 Identification of Hundreds of UPF1 Targets by Determining the Stability of Whole Transcriptome in Mammalian Cells Nobuyoshi Akimitsu (The University of Tokyo, Japan) P03 The Selective Constraint on the Sizes of Insertions and Deletions in 5’ Untranslated Regions in Mammals Feng-Chi Chen (National Health Research Institutes, Taiwan) P04 High Expression Level of Tra2-beta1 is Responsible for Increased SMN2 Exon 7 Inclusion in the Testis of SMA Mice Yu-Chia Chen (Kaohsiung Medical University, Taiwan) P05 Molecular Function of a Novel RNA Binding Protein in Embryonic and Mature Endoderm Cells Nicolas Fossat (Children's Medical Research Institute, Australia) P06 microRNAs Block Translation Initiation via GW182-dependent and -independent Pathways Takashi Fukaya (The University of Tokyo, Japan) P07 Canonical A-to-I and C-to-U RNA Editing is Abundant in Multiple Mouse Tissues Tongjun Gu (The Jackson Laboratory, USA) P08 mRNA-targeted Gene Regulation with 2'-OMe RNA Containing 2-Amino-6-vinylpurine Shinya Hagihara (Tohoku University, Japan) P09 Pgc Protects Germ Plasm RNAs from MicroRNA-Mediated Degradation in Drosophila Primordial Germ Cells Kazuko Hanyu-Nakamura (RIKEN Center for Developmental Biology, Japan) P10 Plant PolyA Specific Ribonuclease (PARN) is Involved in the Regulation of Mitochondrial mRNA PolyA Status Takashi Hirayama (Okayama University, Japan) P11 Characterization of Virus-induced RNA Seckle in the Nucleus Tomoyuki Honda (Kyoto University, Japan) P12 A Noncoding Imprinted RNA, MESTIT1 is Essential for the Repression in cis of KLF14 Shin-ichi Horike (Kanazawa University, Japan) P13 Modulating SMN2 Exon 7 Splicing by the Compounds that Increase Tra2-beta1 Protein Expression in Neuron Cells Wei-Che Hsiao (Kaohsiung Medical University, Taiwan) P14 Small RNAs Derived from the 5' End of tRNA can Inhibit Translation without the Need for Complementary Target Sites Gyorgy Hutvagner (University of Technology, Sydney, Australia) P15 Distinct Mechanisms of NGDs by Road-block of Ribosome and Translation Arrest Ken Ikeuchi (Tohoku University, Japan) P16 Physiological Roles of MRE32 RNA in Drosophila Optic Lobe and Wing Development Sachi Inagaki (Kobe University, Japan) P17 Intrinsic Nucleic Acid-Binding Activity of Chp1 Chromodomain is Required for Heterochromatin Assembly Mayumi Ishida (RIKEN Center for Developmental Biology, Japan) P18 Mechanism of Small RNA-Mediated Translational Repression in Plants Hiro-oki Iwakawa (The University of Tokyo, Japan) P19 In vitro Reconstitution of RISC Assembly Mediated by Hsc70/Hsp90 Chaperone Machinery Shintaro Iwasaki (The University of Tokyo, Japan) P20 Transcriptional and Post-transcriptional Processes Contribute to Allele-specific Gene Expression Variation in the Human Genome Mitsutaka Kadota (RIKEN Center for Developmental Biology, Japan) Top P21 PUF60 is a Differentiation-Dependent Splicing Regulator Required for Myogenesis Naoyuki Kataoka (Kyoto University, Japan) P22 Edc3, a P-body Component, is Required for oskar mRNA Localization and Translation during Drosophila Oogenesis Yasuko Kato (RIKEN Center for Developmental Biology, Japan) P23 Stabilisation of Human Interferon-α1 mRNA by its Antisense RNA Tominori Kimura (Ritsumeikan University, Japan) P24 40S Subunit Dissociation and Proteasome-dependent RNA Degradation in Nonfunctional 25S rRNA Decay Makoto Kitabatake (Kyoto University, Japan) P25 Biogenesis of Small RNAs Associating with Rice MEL1, a Germ-Cell-Specific Argonaute Protein Reina Komiya (National Institute of Genetics, Japan) P26 Natural Sense-Antisense Transcripts Originated from zic3-zic6 Locus in Zebrafish Igor Kondrychyn (Institute of Molecular and Cell Biology, Singapore) P27 Identification and Characterization of Long Non-coding RNAs Differentially Expressed upon Innate Immune Responses Yutaro Kumagai (Osaka University, Japan) P28 Transcriptomic/Deep Sequencing Analysis Reveal the Functional Roles of Trans-spliced RNA in Pluripotency Maintanience and Early Lineage Differentiation Hung-Chih Kuo (Academia Sinica, Taiwan) P29 Characterization of Natural Compounds that Affect Nuclear Speckle Formation and Alternative Pre-mRNA Splicing in Mammalian Cells Yutaro Kurogi (Kumamoto University, Japan) P30 CELF Family RNA-binding Protein UNC-75 Regulates Neuron-specific Alternative Splicing in C. elegans Hidehito Kuroyanagi (Tokyo Medical and Dental University, Japan) P31 Heat Stress Induces the Co-aggregation of Drosophila P-body Components with Stress Granules in Nurse Cells Ming-Der Lin (Tzu-Chi University, Taiwan) P32 Tethered TNRC6 Stimulates mRNA Decay Independent of Translation and Poly(A) Tail in Yeast Shiho Makino (Tohoku University, Japan) P33 Regnase-1 Associates with Ribosome and Destabilizes Translationally Active mRNAs Takashi Mino (Osaka University, Japan) P34 Molecular Mechanisms of MicroRNA-mediated Gene Silencing during Zebrafish Embryogenesis Yuichiro Mishima (Kobe University, Japan) P35 Nuclear Noncoding RNA Neat1 Regulates Corpus Luteum Development in Aged Animals Shinichi Nakagawa (RIKEN Advanced Science Institute, Japan) P36 Analysis of Intracellular Localization of Viral RNA Sensor, RLR Koji Onomoto (Chiba University, Japan) P37 Translation Control by Light Shinzi Ogasawara (RIKEN, Japan) P38 X-inactivation Triggered by Xist RNA Deleted for the 5' Sequence in the Mouse Embryo Takashi Sado (Kyushu University, Japan) P39 RNA Surveillance is Required for Endoplasmic Reticulum Homeostasis Kenjiro Sakaki (Tokyo Women's Medical University, Japan) P40 Identification of Axonal microRNAs Reveals Involvement of miR-720 in Neurotrophin-regulated Axonal Growth Yukio Sasaki (Yokohama City University, Japan) Top P41 Regulation of MAPK Signaling by Nuclear-Cytoplasmic Shuttling of the RNA-Binding Protein Rnc1 in Fission Yeast Ryosuke Satoh (Institute of Microbial Chemistry, Japan) P42 RNA-Binding Proteins Regulating Pluripotent Somatic Stem Cells in a Planarian, Dugesia japonica Norito Shibata (Kyoto University, Japan) P43 EJC Core Subunits have a Novel Gatekeeper Function in mRNA Quality Control in the Nematode C. elegans Masami Shiimori (Kobe University, Japan) P44 MAPK Signaling and RNA-granules Formation in Fission yeast Reiko Sugiura (Kinki University, Japan) P45 Red5: An Essential Factor for Selective Elimination of Meiotic mRNAs in Vegetative Fission Yeast Tomo Sugiyama (University of Tsukuba, Japan) P46 Sqt RNA and its Localization Machinery Arvindakshan Sundaram (Temasek Life Sciences Laboratory, Singapore) P47 Single Molecule Imaging of the trans-translation Entry Process on Anchored Ribosome Hisashi Tadakuma (The University of Tokyo, Japan) P48 Distinguishable In Vitro Binding Mode of TRBP and PACT with siRNA Tomoko Takahashi (The University of Tokyo, Japan) P49 The Essential Role for RNA Triphosphatase Cet1p in Transport of Capping Enzyme in Saccharomyces cerevisiae Naoki Takizawa (Institute of Microbial Chemistry, Japan) P50 Genome-wide Determination of RNA Stability Reveals Hundreds of Short-lived Noncoding Transcripts in Mammals Hidenori Tani (National Institute of Advanced Industrial Science and Technology (AIST), Japan) P51 A Molecular Machinery that Determines Alternative Splicing Patterns of Insulin Receptor in C. elegans Chemosensory Neurons Masahiro Tomioka (The University of Tokyo, Japan) P52 An Endogenous Target of NGD: CBP1 mRNA Tatsuhisa Tsuboi (Tohoku University, Japan) P53 SKIP P54 Species-Specific Pseudogene Insertions Generate Cis-Acting RNA for Promoter Demethylation in the Macaque Masahiro Uesaka (Kyoto University, Japan) P55 Identification of mRNA Targeting to the ER Takanari Umegawachi (Kyoto Institute of Technology, Japan) P56 In vivo RNA Imaging with Hybridization-sensitive Fluorescent Oligonucleotide Probes Dan Ohtan Wang (Kyoto University, Japan) P57 Functional Analysis of Vasa RNA Helicase in Drosophila Oogenesis Szu-Chieh Wang (Tzu-Chi University, Taiwan) P58 Mex-3B, a KH-type RNA-binding Protein, is Required for IL-33 Production in the Development of Allergic Airway Inflammation Yusuke Yamazumi (The University of Tokyo, Japan) P59 Translational Regulation of Mouse Interferon Beta mRNA via the AU-Rich Elements, the mRNA Poly(A) Tail and Poly(A)-Binding Protein Akiko Yanagiya (McGill University, Canada) P60 Biochemical Characterization of Dicer-independent miR-451 Biogenesis Mayuko Yoda (The University of Tokyo, Japan) Top
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