Here is the list of knock-out (KO) and knock-in (KI) mouse lines generated by gene targeting in ES cells at LARGE as collaborations with investigators at CDB and a number of other academic institutions. These KO/KI mutant mouse lines are available to the scientific community. Please follow the "Detail" link for further information. To request the mutant mouse line of your interest, please contact "mutant(at)cdb.riken.jp".