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Date and Time 2017-09-28 16:00 - 17:00
Venue Seminar Room A7F
Speaker Luis Morelli
Affiliation Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA), CONICET - Partner Institute of the Max Planck Society
Title [QBiC-CDB Joint Seminar] Collective oscillations in the zebrafish segmentation clock
Poster click here to download(PDF)
Host Miki Ebisuya
Abstract Cells generate, process and share information to orchestrate the patterning of tissues and organs during embryonic development. An interesting example is vertebrate segmentation, where the axis going from head to tail is subdivided into regular segments that will later form the vertebrae and other tissues. This segmentation is rhythmic, and it is thought that a gene regulatory network is responsible for the rhythm at the cellular level. At a local level, intercellular signaling communicates cells and synchronizes them into a collective oscillation. This collective oscillation produces gene expression waves that traverse the unsegmented tissue and give rise to segments. In this talk I will discuss some findings about how this collective rhythm is organized, from an interdisciplinary perspective that brings together theory and experiment.
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