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Category CDBセミナー
Date and Time 2016-09-14 16:00 - 17:00
Venue Auditorium C1F
Speaker Richard Behringer
Affiliation Department of Genetics, The University of Texas MD Anderson Cancer Center
Title Developmental Genetics of Mammalian Reproductive Organs
Poster click here to download(PDF)
Host Yasuhide Furuta
abstract The mammalian female reproductive organs are essential for fertility and are a common site or source of disease. Developmental, experimental embryological and time lapse-imaging studies will be presented to understand the molecular and cellular mechanisms that regulate the formation of the uterus and oviducts from a simple epithelial tube with associated mesenchyme. The progenitor tissue of the uterus and oviducts also forms in genetic males but is eliminated by hormones secreted by the fetal testis. We are defining the molecular pathway from the fetal testis to regression of the uterine/oviductal progenitor tissues during male sexual differentiation. Defects in the differentiation of the male and females phenotypes can lead to disorders of sexual development.
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