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Category CDBセミナー
Date and Time 2015-08-18 16:00 - 17:00
Venue Seminar Room A7F
Speaker Mitsuyoshi Nakao
Affiliation Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University
Title Epigenetic reprogramming in cancer and energy metabolism (4th Epigenetics Seminar Series 2015)
Poster click here to download(PDF)
Host Ichiro Hiratani
Abstract Modifications on DNA and histones are stably maintained for cell identity. In addition, gene activities at each chromosomal locus are controlled by the regulatory elements such as the enhancer-promoter-insulator and further by the higher-order chromatin formation in the nuclear context. These epigenetic states are occasionally reset by environmental factors, and may be inherited as the cellular memory. This seminar will highlight the non-coding RNA-mediated mechanism in cancer cell adaptation, and the metabolic regulation by the lysine-specific demethylase LSD1.
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