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Category | CDBセミナー |
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Date and Time | 2010-11-11 16:00 - 17:00 |
Venue | Auditorium C1F |
Speaker | Juergen A. Knoblich |
Affiliation | Institute of Molecular Biotechnology of the Austrian Academy of Sciences(IMBA) |
Title | Asymmetric cell division and tumorigenesis in Drosophila neural stem cell lineages |
Poster | click here to download(PDF) |
Host | Fumio Matsuzaki |
Profile | Dr. Knoblich is a distinguished scientist in the field of Drosophila cell biology. He has and continues to make major contributions in our understanding of the mechanisms underlying cell polarity and asymmetric cell division, using neural stem cells, neuroblasts, as a model. He has also developed neuroblasts as a model system for stem cell cancer. Recently he has extended his study to mammalian neural stem cells and discovered that a protein family, which includes Drosophila tumor suppressor Brat and Mei P-26, regulates microRNA activity to balance differentiation and proliferation in stem cell lineages in both Drosophila and mouse. This time he is visiting Japan to participate in a symposium in Kyoto. He will be coming to give a talk at the CDB, focusing on the relationship of asymmetric cell division and tumorigenesis. |